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Novel aspects of regulatory T cell dysfunction as a therapeutic target in giant cell arteritis
OBJECTIVES: Giant cell arteritis (GCA) is the most common primary vasculitis, preferentially affecting the aorta and its large-calibre branches. An imbalance between proinflammatory CD4(+) T helper cell subsets and regulatory T cells (Tregs) is thought to be involved in the pathogenesis of GCA and T...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762021/ https://www.ncbi.nlm.nih.gov/pubmed/34583923 http://dx.doi.org/10.1136/annrheumdis-2021-220955 |