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Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis

OBJECTIVE: A detailed understanding of the molecular alterations in different forms of cholangiocarcinogenesis is crucial for a better understanding of cholangiocarcinoma (CCA) and may pave the way to early diagnosis and better treatment options. DESIGN: We analysed a clinicopathologically well-char...

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Detalles Bibliográficos
Autores principales: Goeppert, Benjamin, Stichel, Damian, Toth, Reka, Fritzsche, Sarah, Loeffler, Moritz Anton, Schlitter, Anna Melissa, Neumann, Olaf, Assenov, Yassen, Vogel, Monika Nadja, Mehrabi, Arianeb, Hoffmann, Katrin, Köhler, Bruno, Springfeld, Christoph, Weichenhan, Dieter, Plass, Christoph, Esposito, Irene, Schirmacher, Peter, von Deimling, Andreas, Roessler, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762040/
https://www.ncbi.nlm.nih.gov/pubmed/33468537
http://dx.doi.org/10.1136/gutjnl-2020-322983