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Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways

This study investigated the effect and mechanism of chrysosplenol D (CD) on LPS-induced acute lung injury in mice. Histological changes in the lungs were measured by hematoxylin-eosin staining. The levels of IL-6, IL-1β, and TNF-α in the bronchoalveolar lavage fluid were detected by ELISA. The level...

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Detalles Bibliográficos
Autores principales: Zhang, Qinqin, Feng, Aozi, Zeng, Mengnan, Zhang, Beibei, Shi, Jingya, Lv, Yaxin, Cao, Bing, Zhao, Chenxin, Wang, Mengya, Ding, Yifan, Zheng, Xiaoke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762090/
https://www.ncbi.nlm.nih.gov/pubmed/34806444
http://dx.doi.org/10.1177/17534259211051069