Cargando…

Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways

This study investigated the effect and mechanism of chrysosplenol D (CD) on LPS-induced acute lung injury in mice. Histological changes in the lungs were measured by hematoxylin-eosin staining. The levels of IL-6, IL-1β, and TNF-α in the bronchoalveolar lavage fluid were detected by ELISA. The level...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Qinqin, Feng, Aozi, Zeng, Mengnan, Zhang, Beibei, Shi, Jingya, Lv, Yaxin, Cao, Bing, Zhao, Chenxin, Wang, Mengya, Ding, Yifan, Zheng, Xiaoke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762090/ https://www.ncbi.nlm.nih.gov/pubmed/34806444 http://dx.doi.org/10.1177/17534259211051069

Ejemplares similares

Resveratrol inhibits LPS-induced inflammation through suppressing the signaling cascades of TLR4-NF-κB/MAPKs/IRF3
por: Tong, Wenzhi, et al.
Publicado: (2020)

Chrysosplenol D can inhibit the growth of prostate cancer by inducing reactive oxygen species and autophagy
por: Zhang, Haoyu, et al.
Publicado: (2023)

Protopine Protects Mice against LPS-Induced Acute Kidney Injury by Inhibiting Apoptosis and Inflammation via the TLR4 Signaling Pathway
por: Zhang, Beibei, et al.
Publicado: (2019)

Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-κB and MAPK Pathways in LPS-Stimulated BV-2 Microglia
por: Li, Baojing, et al.
Publicado: (2022)

TRDMT1 exhibited protective effects against LPS‐induced inflammation in rats through TLR4‐NF‐κB/MAPK‐TNF‐α pathway
por: Li, Zhengguang, et al.
Publicado: (2022)

Baicalin Relieves LPS-Induced Lung Inflammation via the NF-κB and MAPK Pathways
por: Shen, Bingyu, et al.
Publicado: (2023)

Polygonatum Polysaccharide Regulates Macrophage Polarization and Improves LPS-Induced Acute Lung Injury through TLR4-MAPK/NF-κB Pathway
por: Zhou, Weizheng, et al.
Publicado: (2022)

Lysophosphatidylcholine Triggers TLR2- and TLR4-Mediated Signaling Pathways but Counteracts LPS-Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-κB Translocation and MAPK/ERK Phosphorylation
por: Carneiro, Alan Brito, et al.
Publicado: (2013)

Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis
por: Qu, Yifan, et al.
Publicado: (2021)

NF-κB inhibition attenuates LPS-induced TLR4 activation in monocyte cells
por: Wan, Jian, et al.
Publicado: (2016)

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
por: Wang, Huanhuan, et al.
Publicado: (2018)

Epiisopiloturine, an Alkaloid from Pilocarpus microphyllus, Attenuates LPS-Induced Neuroinflammation by Interfering in the TLR4/NF-κB-MAPK Signaling Pathway in Microglial Cells
por: de Sousa, João Antônio Costa, et al.
Publicado: (2023)

Corilagin ameliorates macrophages inflammation in atherosclerosis through TLR4-NFκB/MAPK pathway
por: Meng, Da, et al.
Publicado: (2023)

Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways
por: Li, Rui, et al.
Publicado: (2019)

Anti-inflammation of isoliquiritigenin via the inhibition of NF-κB and MAPK in LPS-stimulated MAC-T cells
por: Li, Manman, et al.
Publicado: (2022)

Adenosine Attenuates LPS-Induced Cardiac Dysfunction by Inhibition of Mitochondrial Function via the ER Pathway
por: Zeng, Mengnan, et al.
Publicado: (2019)

Frutescone O from Baeckea frutescens Blocked TLR4-Mediated Myd88/NF-κB and MAPK Signaling Pathways in LPS Induced RAW264.7 Macrophages
por: Lin, Xiaobing, et al.
Publicado: (2021)

A sesquiterpene isolated from the stems and leaves of Dioscorea opposita thunb. Transforms the composition of immune cells through ERβ in a mouse model of LPS-induced lung injury
por: Zeng, Mengnan, et al.
Publicado: (2022)

α-Mangostin inhibits LPS-induced bone resorption by restricting osteoclastogenesis via NF-κB and MAPK signaling
por: Zhang, Wenkan, et al.
Publicado: (2022)

Ugonin M, a Helminthostachys zeylanica Constituent, Prevents LPS-Induced Acute Lung Injury through TLR4-Mediated MAPK and NF-κB Signaling Pathways
por: Wu, Kun-Chang, et al.
Publicado: (2017)

Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway
por: Xiang, Nan-lin, et al.
Publicado: (2016)

Tacrolimus alleviates LPS‐induced AKI by inhibiting TLR4/MyD88/NF‐κB signalling in mice
por: Hu, Xueqing, et al.
Publicado: (2021)

Sorafenib inhibits LPS-induced inflammation by regulating Lyn-MAPK-NF-kB/AP-1 pathway and TLR4 expression
por: Li, Xiaolian, et al.
Publicado: (2022)

Exopolysaccharide from Paecilomyces lilacinus modulates macrophage activities through the TLR4/NF-κB/MAPK pathway
por: He, Chao, et al.
Publicado: (2019)

LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF
por: Fitzgerald, Katherine A., et al.
Publicado: (2003)

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway
por: Badshah, Haroon, et al.
Publicado: (2016)

Prolactin decreases LPS-induced inflammatory cytokines by inhibiting TLR-4/NFκB signaling in the human placenta
por: Olmos-Ortiz, A, et al.
Publicado: (2019)

THE ALARMIN EFFECT OF HMGB1/RIP3 ON TRANSFUSION-RELATED ACUTE LUNG INJURY VIA TLR4/NF-ΚB OR MAPK PATHWAY
por: Liu, Shuangchun, et al.
Publicado: (2023)

Decursinol Angelate Inhibits LPS-Induced Macrophage Polarization through Modulation of the NFκB and MAPK Signaling Pathways
por: Islam, Salman Ul, et al.
Publicado: (2018)

Neoagaro-oligosaccharide monomers inhibit inflammation in LPS-stimulated macrophages through suppression of MAPK and NF-κB pathways
por: Wang, Wei, et al.
Publicado: (2017)

Anti-Inflammatory Activity of Oligomeric Proanthocyanidins Via Inhibition of NF-κB and MAPK in LPS-Stimulated MAC-T Cells
por: Ma, Xiao, et al.
Publicado: (2020)

Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-κB and MAPK Signaling
por: Tang, Yongjun, et al.
Publicado: (2018)

Four New Benzoylamide Derivatives Isolated from the Seeds of Lepidium apetalum Willd. and Ameliorated LPS-Induced NRK52e Cells via Nrf2/Keap1 Pathway
por: Li, Meng, et al.
Publicado: (2022)

GBE50 Attenuates Inflammatory Response by Inhibiting the p38 MAPK and NF-κB Pathways in LPS-Stimulated Microglial Cells
por: He, Gai-ying, et al.
Publicado: (2014)

Lactobacillus plantarum Lp2 improved LPS-induced liver injury through the TLR-4/MAPK/NFκB and Nrf2-HO-1/CYP2E1 pathways in mice
por: Chen, Yiying, et al.
Publicado: (2022)

Epimedium sagittatum Maxim ameliorates adriamycin‐induced nephropathy by restraining inflammation and apoptosis via the PI3K/AKT signaling pathway
por: Wang, Ru, et al.
Publicado: (2023)

Allicin Alleviated LPS-Induced Mastitis via the TLR4/NF-κB Signaling Pathway in Bovine Mammary Epithelial Cells
por: Che, Hao-Yu, et al.
Publicado: (2023)

Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways
por: Yuan, Qing, et al.
Publicado: (2022)

ISGylation Inhibits an LPS-Induced Inflammatory Response via the TLR4/NF-κB Signaling Pathway in Goat Endometrial Epithelial Cells
por: Xiao, Jinbang, et al.
Publicado: (2021)

Procyanidin A1 Alleviates Inflammatory Response induced by LPS through NF-κB, MAPK, and Nrf2/HO-1 Pathways in RAW264.7 cells
por: Han, Shan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5q5n061r5tqj52divb068jr6fk