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TLRs in COVID-19: How they drive immunopathology and the rationale for modulation

COVID-19 is both a viral illness and a disease of immunopathology. Proximal events within the innate immune system drive the balance between deleterious inflammation and viral clearance. We hypothesize that a divergence between the generation of excessive inflammation through over activation of the...

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Detalles Bibliográficos
Autores principales: Mabrey, F. Linzee, Morrell, Eric D, Wurfel, Mark M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762091/
https://www.ncbi.nlm.nih.gov/pubmed/34806446
http://dx.doi.org/10.1177/17534259211051364