Large-scale manufacturing and characterization of CMV-CD19CAR T cells

BACKGROUND: Adoptive transfer of CD19-specific chimeric antigen receptor (CD19CAR) T cells can induce dramatic disease regression in patients with B cell malignancies. CD19CAR T cell therapy may be limited by insufficient engraftment and persistence, resulting in tumor relapse. We previously demonst...

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Detalles Bibliográficos
Autores principales: Wang, Xiuli, Urak, Ryan, Walter, Miriam, Guan, Min, Han, Tianxu, Vyas, Vibhuti, Chien, Sheng-Hsuan, Gittins, Brenna, Clark, Mary C, Mokhtari, Sally, Cardoso, Angelo, Diamond, Don J, Zaia, John, Forman, Stephen J, Nakamura, Ryotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762141/
https://www.ncbi.nlm.nih.gov/pubmed/35027426
http://dx.doi.org/10.1136/jitc-2021-003461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762141/
https://www.ncbi.nlm.nih.gov/pubmed/35027426
http://dx.doi.org/10.1136/jitc-2021-003461

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