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5-HT(3) Receptor Antagonism: A Potential Therapeutic Approach for the Treatment of Depression and other Disorders

BACKGROUND: Depression or Major depressive disorder (MDD) is a prolonged condition of sadness. MDD is the most common mental disorder that affects more than 264 million people worldwide. According to the monoamine hypothesis, serotonin (5-hydroxy tryptamine, 5-HT), dopamine (DA) and norepinephrine (...

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Detalles Bibliográficos
Autores principales: Bhatt, Shvetank, Devadoss, Thangaraj, Manjula, Santhepete Nanjundaiah, Rajangam, Jayaraman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762176/
https://www.ncbi.nlm.nih.gov/pubmed/33059577
http://dx.doi.org/10.2174/1570159X18666201015155816