Cargando…
5-HT(3) Receptor Antagonism: A Potential Therapeutic Approach for the Treatment of Depression and other Disorders
BACKGROUND: Depression or Major depressive disorder (MDD) is a prolonged condition of sadness. MDD is the most common mental disorder that affects more than 264 million people worldwide. According to the monoamine hypothesis, serotonin (5-hydroxy tryptamine, 5-HT), dopamine (DA) and norepinephrine (...
Autores principales: | Bhatt, Shvetank, Devadoss, Thangaraj, Manjula, Santhepete Nanjundaiah, Rajangam, Jayaraman |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762176/ https://www.ncbi.nlm.nih.gov/pubmed/33059577 http://dx.doi.org/10.2174/1570159X18666201015155816 |
Ejemplares similares
-
Antidepressant-like effect of novel 5-HT3 receptor antagonist N-n-butyl-3-ethoxyquinoxalin-2-carboxamide (6p): An approach using rodent behavioral antidepressant tests
por: Bhatt, Shvetank, et al.
Publicado: (2013) -
Antidepressant-like activity of (4-phenylpiperazin-1-yl) (quinoxalin-2-yl) methanone (4a), a novel 5-HT(3) receptor antagonist: An investigation in behaviour-based rodent models of depression
por: Mahesh, Radhakrishnan, et al.
Publicado: (2012) -
Neuropharmacological evaluation of a novel 5-HT(3) receptor antagonist (6g) on chronic unpredictable mild stress-induced changes in behavioural and brain oxidative stress parameters in mice
por: Bhatt, Shvetank, et al.
Publicado: (2014) -
Anxiolytic-like effect of (4-benzylpiperazin-1-yl)(3-methoxyquinoxalin-2-yl)methanone (6g) in experimental mouse models of anxiety
por: Bhatt, Shvetank, et al.
Publicado: (2013) -
Role of Hypothalamic-pituitary-adrenal-axis in Affective Disorders: Anti-depressant and Anxiolytic Activity of Partial 5-HT1A Agonist in Adrenalectomised Rats
por: Gupta, Deepali, et al.
Publicado: (2013)