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Acid-Sensing Ion Channels: Focus on Physiological and Some Pathological Roles in the Brain

Acid-sensing ion channels (ASICs) are Na(+)-permeable ion channels activated by protons and predominantly expressed in the nervous system. ASICs act as pH sensors leading to neuronal excitation. At least eight different ASIC subunits (including ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, ASIC4, ASIC5) ar...

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Detalles Bibliográficos
Autores principales: Storozhuk, Maksim, Cherninskyi, Andrii, Maximyuk, Oleksandr, Isaev, Dmytro, Krishtal, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762183/
https://www.ncbi.nlm.nih.gov/pubmed/33550975
http://dx.doi.org/10.2174/1570159X19666210125151824