Impaired JAK-STAT pathway signaling in leukocytes of the frail elderly

BACKGROUND: Elderly often show reduced immune functioning and can develop chronic low-grade inflammation. Why some elderly are more prone to become frail is unknown. We investigated whether frailty is associated with altered cytokine signaling through the JAK-STAT pathway in leukocytes of 34 individ...

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Detalles Bibliográficos
Autores principales: Samson, Leonard Daniël, Engelfriet, Peter, Verschuren, W. M. Monique, Picavet, H. Susan J., Ferreira, José A., de Zeeuw-Brouwer, Mary-lène, Buisman, Anne-Marie, Boots, A. Mieke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762193/
https://www.ncbi.nlm.nih.gov/pubmed/35039055
http://dx.doi.org/10.1186/s12979-021-00261-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762193/
https://www.ncbi.nlm.nih.gov/pubmed/35039055
http://dx.doi.org/10.1186/s12979-021-00261-w

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