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Machine Learning Identifies Six Genetic Variants and Alterations in the Heart Atrial Appendage as Key Contributors to PD Risk Predictivity

Parkinson’s disease (PD) is a complex neurodegenerative disease with a range of causes and clinical presentations. Over 76 genetic loci (comprising 90 SNPs) have been associated with PD by the most recent GWAS meta-analysis. Most of these PD-associated variants are located in non-coding regions of t...

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Detalles Bibliográficos
Autores principales: Ho, Daniel, Schierding, William, Farrow, Sophie L., Cooper, Antony A., Kempa-Liehr, Andreas W., O’Sullivan, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762216/
https://www.ncbi.nlm.nih.gov/pubmed/35047012
http://dx.doi.org/10.3389/fgene.2021.785436