Cargando…
Machine Learning Identifies Six Genetic Variants and Alterations in the Heart Atrial Appendage as Key Contributors to PD Risk Predictivity
Parkinson’s disease (PD) is a complex neurodegenerative disease with a range of causes and clinical presentations. Over 76 genetic loci (comprising 90 SNPs) have been associated with PD by the most recent GWAS meta-analysis. Most of these PD-associated variants are located in non-coding regions of t...
Autores principales: | Ho, Daniel, Schierding, William, Farrow, Sophie L., Cooper, Antony A., Kempa-Liehr, Andreas W., O’Sullivan, Justin M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762216/ https://www.ncbi.nlm.nih.gov/pubmed/35047012 http://dx.doi.org/10.3389/fgene.2021.785436 |
Ejemplares similares
-
Machine Learning SNP Based Prediction for Precision Medicine
por: Ho, Daniel Sik Wai, et al.
Publicado: (2019) -
The missing story behind Genome Wide Association Studies: single nucleotide polymorphisms in gene deserts have a story to tell
por: Schierding, William, et al.
Publicado: (2014) -
Establishing gene regulatory networks from Parkinson’s disease risk loci
por: Farrow, Sophie L, et al.
Publicado: (2022) -
Physical Interactions and Expression Quantitative Traits Loci Identify Regulatory Connections for Obesity and Type 2 Diabetes Associated SNPs
por: Fadason, Tayaza, et al.
Publicado: (2017) -
A Review of Feature Selection Methods for Machine Learning-Based Disease Risk Prediction
por: Pudjihartono, Nicholas, et al.
Publicado: (2022)