Ginsenoside Rb1 Attenuates Triptolide-Induced Cytotoxicity in HL-7702 Cells via the Activation of Keap1/Nrf2/ARE Pathway

Triptolide (TP) is the major bioactive compound extracted from Tripterygium wilfordii Hook F. It exerts anti-inflammatory, antirheumatic, antineoplastic, and neuroprotective effects. However, the severe hepatotoxicity induced by TP limits its clinical application. Ginsenoside Rb1 has been reported t...

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Detalles Bibliográficos
Autores principales: Peng, Hulinyue, You, Longtai, Yang, Chunjing, Wang, Kaixin, Liu, Manting, Yin, Dongge, Xu, Yuchen, Dong, Xiaoxv, Yin, Xingbin, Ni, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762226/
https://www.ncbi.nlm.nih.gov/pubmed/35046796
http://dx.doi.org/10.3389/fphar.2021.723784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762226/
https://www.ncbi.nlm.nih.gov/pubmed/35046796
http://dx.doi.org/10.3389/fphar.2021.723784

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