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Ginsenoside Rb1 Attenuates Triptolide-Induced Cytotoxicity in HL-7702 Cells via the Activation of Keap1/Nrf2/ARE Pathway
Triptolide (TP) is the major bioactive compound extracted from Tripterygium wilfordii Hook F. It exerts anti-inflammatory, antirheumatic, antineoplastic, and neuroprotective effects. However, the severe hepatotoxicity induced by TP limits its clinical application. Ginsenoside Rb1 has been reported t...
Autores principales: | Peng, Hulinyue, You, Longtai, Yang, Chunjing, Wang, Kaixin, Liu, Manting, Yin, Dongge, Xu, Yuchen, Dong, Xiaoxv, Yin, Xingbin, Ni, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762226/ https://www.ncbi.nlm.nih.gov/pubmed/35046796 http://dx.doi.org/10.3389/fphar.2021.723784 |
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