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Comparative Evaluation of the Effect of Metformin and Insulin on Gut Microbiota and Metabolome Profiles of Type 2 Diabetic Rats Induced by the Combination of Streptozotocin and High-Fat Diet

Lately, an increasing number of studies have investigated the relationship between metformin and gut microbiota, suggesting that metformin exerts part of its hypoglycemic effect through the microbes. However, its underlying mechanism remains largely undetermined. In the present study, we investigate...

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Detalles Bibliográficos
Autores principales: Hu, Nan, Zhang, Qi, Wang, Hui, Yang, Xuping, Jiang, Yan, Chen, Rong, Wang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762251/
https://www.ncbi.nlm.nih.gov/pubmed/35046817
http://dx.doi.org/10.3389/fphar.2021.794103