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Comparative Evaluation of the Effect of Metformin and Insulin on Gut Microbiota and Metabolome Profiles of Type 2 Diabetic Rats Induced by the Combination of Streptozotocin and High-Fat Diet
Lately, an increasing number of studies have investigated the relationship between metformin and gut microbiota, suggesting that metformin exerts part of its hypoglycemic effect through the microbes. However, its underlying mechanism remains largely undetermined. In the present study, we investigate...
Autores principales: | Hu, Nan, Zhang, Qi, Wang, Hui, Yang, Xuping, Jiang, Yan, Chen, Rong, Wang, Liying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762251/ https://www.ncbi.nlm.nih.gov/pubmed/35046817 http://dx.doi.org/10.3389/fphar.2021.794103 |
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