Imputation Performance in Latin American Populations: Improving Rare Variants Representation With the Inclusion of Native American Genomes

Current Genome-Wide Association Studies (GWAS) rely on genotype imputation to increase statistical power, improve fine-mapping of association signals, and facilitate meta-analyses. Due to the complex demographic history of Latin America and the lack of balanced representation of Native American geno...

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Detalles Bibliográficos
Autores principales: Jiménez-Kaufmann, Andrés, Chong, Amanda Y., Cortés, Adrián, Quinto-Cortés, Consuelo D., Fernandez-Valverde, Selene L., Ferreyra-Reyes, Leticia, Cruz-Hervert, Luis Pablo, Medina-Muñoz, Santiago G., Sohail, Mashaal, Palma-Martinez, María J., Delgado-Sánchez, Gudalupe, Mongua-Rodríguez, Norma, Mentzer, Alexander J., Hill, Adrian V. S., Moreno-Macías, Hortensia, Huerta-Chagoya, Alicia, Aguilar-Salinas, Carlos A., Torres, Michael, Kim, Hie Lim, Kalsi, Namrata, Schuster, Stephan C., Tusié-Luna, Teresa, Del-Vecchyo, Diego Ortega, García-García, Lourdes, Moreno-Estrada, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762266/
https://www.ncbi.nlm.nih.gov/pubmed/35046991
http://dx.doi.org/10.3389/fgene.2021.719791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762266/
https://www.ncbi.nlm.nih.gov/pubmed/35046991
http://dx.doi.org/10.3389/fgene.2021.719791

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