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Dihydroartemisinin-Transferrin Adducts Enhance TRAIL-Induced Apoptosis in Triple-Negative Breast Cancer in a P53-Independent and ROS-Dependent Manner

Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype independent of estrogen receptor, progesterone receptor, or human epidermal growth factor receptor 2. It has a poor prognosis and high recurrence. Due to its limited treatment options in the clinic, novel therapies are...

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Detalles Bibliográficos
Autores principales: Zhou, Xinyu, Soto-Gamez, Abel, Nijdam, Fleur, Setroikromo, Rita, Quax, Wim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762273/
https://www.ncbi.nlm.nih.gov/pubmed/35047402
http://dx.doi.org/10.3389/fonc.2021.789336