In silico Cell Therapy Model Restores Failing Human Myocyte Electrophysiology and Calcium Cycling in Fibrotic Myocardium

Myocardial delivery of human c-kit(+) cardiac interstitial cells (hCICs) and human mesenchymal stem cells (hMSCs), an emerging approach for treating the failing heart, has been limited by an incomplete understanding of the effects on host myocardium. This computational study aims to model hCIC and h...

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Detalles Bibliográficos
Autores principales: Phillips, Katherine G., Turnbull, Irene C., Hajjar, Roger J., Costa, Kevin D., Mayourian, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762340/
https://www.ncbi.nlm.nih.gov/pubmed/35046835
http://dx.doi.org/10.3389/fphys.2021.755881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762340/
https://www.ncbi.nlm.nih.gov/pubmed/35046835
http://dx.doi.org/10.3389/fphys.2021.755881

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