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Fully Characterized Mature Human iPS- and NMP-Derived Motor Neurons Thrive Without Neuroprotection in the Spinal Contusion Cavity

Neural cell interventions in spinal cord injury (SCI) have focused predominantly on transplanted multipotent neural stem/progenitor cells (NSPCs) for animal research and clinical use due to limited information on survival of spinal neurons. However, transplanted NSPC fate is unpredictable and largel...

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Detalles Bibliográficos
Autores principales: Olmsted, Zachary T., Stigliano, Cinzia, Marzullo, Brandon, Cibelli, Jose, Horner, Philip J., Paluh, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762343/
https://www.ncbi.nlm.nih.gov/pubmed/35046774
http://dx.doi.org/10.3389/fncel.2021.725195