OPA1 Modulates Mitochondrial Ca(2+) Uptake Through ER-Mitochondria Coupling

Autosomal Dominant Optic Atrophy (ADOA), a disease that causes blindness and other neurological disorders, is linked to OPA1 mutations. OPA1, dependent on its GTPase and GED domains, governs inner mitochondrial membrane (IMM) fusion and cristae organization, which are central to oxidative metabolism...

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Detalles Bibliográficos
Autores principales: Cartes-Saavedra, Benjamín, Macuada, Josefa, Lagos, Daniel, Arancibia, Duxan, Andrés, María E., Yu-Wai-Man, Patrick, Hajnóczky, György, Eisner, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762365/
https://www.ncbi.nlm.nih.gov/pubmed/35047497
http://dx.doi.org/10.3389/fcell.2021.774108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762365/
https://www.ncbi.nlm.nih.gov/pubmed/35047497
http://dx.doi.org/10.3389/fcell.2021.774108

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