The NRF2-dependent transcriptional axis, XRCC5/hTERT drives tumor progression and 5-Fu insensitivity in hepatocellular carcinoma

Human telomerase reverse transcriptase (hTERT) is highly expressed in many tumors and is essential for tumorigenesis and metastasis in multiple cancers. However, the molecular mechanisms underlying its high expression level in hepatocellular carcinoma (HCC) remain unclear. In this study, we identifi...

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Detalles Bibliográficos
Autores principales: Liu, Tianze, Long, Qian, Li, Luting, Gan, Hairun, Hu, Xinyan, Long, Haoyu, Yang, Lukun, Pang, Pengfei, Wang, Siyang, Deng, Wuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762376/
https://www.ncbi.nlm.nih.gov/pubmed/35071747
http://dx.doi.org/10.1016/j.omto.2021.12.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762376/
https://www.ncbi.nlm.nih.gov/pubmed/35071747
http://dx.doi.org/10.1016/j.omto.2021.12.012

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