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Role of spatial patterns and kinetochore architecture in spindle morphogenesis

Mitotic spindle is a self-assembling macromolecular machine responsible for the faithful segregation of chromosomes during cell division. Assembly of the spindle is believed to be governed by the ‘Search & Capture’ (S&C) principle in which dynamic microtubules explore space in search of kine...

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Detalles Bibliográficos
Autores principales: Renda, Fioranna, Khodjakov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762378/
https://www.ncbi.nlm.nih.gov/pubmed/33836948
http://dx.doi.org/10.1016/j.semcdb.2021.03.016