Endoplasmic reticulum-translocation is essential for APOL1 cellular toxicity

Two variants at the APOL1 gene, encoding apolipoprotein L1, account for more than 70% of the increased risk for chronic kidney disease in individuals of African ancestry. While the initiating event for APOL1 risk variant cell injury remains to be clarified, we explored the possibility of blocking AP...

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Detalles Bibliográficos
Autores principales: Kruzel-Davila, Etty, Bavli-Kertselli, Ira, Ofir, Ayala, Cheatham, Amber M., Shemer, Revital, Zaknoun, Eid, Chornyy, Sergiy, Tabachnikov, Orly, Davis, Shamara E., Khatua, Atanu K., Skorecki, Karl, Popik, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762391/
https://www.ncbi.nlm.nih.gov/pubmed/35072009
http://dx.doi.org/10.1016/j.isci.2021.103717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762391/
https://www.ncbi.nlm.nih.gov/pubmed/35072009
http://dx.doi.org/10.1016/j.isci.2021.103717

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