Ultra-high-throughput Ca(2+) assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation

Antiplatelet drugs targeting G-protein-coupled receptors (GPCRs), used for the secondary prevention of arterial thrombosis, coincide with an increased bleeding risk. Targeting ITAM-linked receptors, such as the collagen receptor glycoprotein VI (GPVI), is expected to provide a better antithrombotic-...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernández, Delia I., Provenzale, Isabella, Cheung, Hilaire Y.F., van Groningen, Jan, Tullemans, Bibian M.E., Veninga, Alicia, Dunster, Joanne L., Honarnejad, Saman, van den Hurk, Helma, Kuijpers, Marijke J.E., Heemskerk, Johan W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762394/
https://www.ncbi.nlm.nih.gov/pubmed/35072010
http://dx.doi.org/10.1016/j.isci.2021.103718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762394/
https://www.ncbi.nlm.nih.gov/pubmed/35072010
http://dx.doi.org/10.1016/j.isci.2021.103718

Ejemplares similares