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OSKM-mediated reversible reprogramming of cardiomyocytes regenerates injured myocardium

Cellular reprogramming has rapidly become a promising methodology to generate new cardiomyocytes from non-cardiomyocyte cell types. Using the transient expression of OSKM factors, Chen et al. demonstrate a unique reprogramming strategy involving the modulation of the resident adult cardiomyocyte ide...

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Detalles Bibliográficos
Autores principales: Farber, Gregory, Liu, Jiandong, Qian, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762525/
https://www.ncbi.nlm.nih.gov/pubmed/35038037
http://dx.doi.org/10.1186/s13619-021-00106-3