MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells

The lipid raft-resident protein, MAL2, has been implicated as contributing to the pathogenesis of several malignancies, including breast cancer, but the underlying mechanism for its effects on tumorigenesis is unknown. Here, we show that MAL2-mediated lipid raft formation leads to HER2 plasma membra...

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Detalles Bibliográficos
Autores principales: Jeong, Jaekwang, Shin, Jae Hun, Li, Wenxue, Hong, Jun Young, Lim, Jaechul, Hwang, Jae Yeon, Chung, Jean-Ju, Yan, Qin, Liu, Yansheng, Choi, Jungmin, Wysolmerski, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762588/
https://www.ncbi.nlm.nih.gov/pubmed/34965434
http://dx.doi.org/10.1016/j.celrep.2021.110160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762588/
https://www.ncbi.nlm.nih.gov/pubmed/34965434
http://dx.doi.org/10.1016/j.celrep.2021.110160

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