Ion Complexation Explains Orders of Magnitude Changes in the Equilibrium Constant of Biochemical Reactions in Buffers Crowded by Nonionic Compounds

[Image: see text] The equilibrium constant (K) of biochemical complex formation in aqueous buffers with high concentration (>20 wt %) of nonionic compounds can vary by orders of magnitude in comparison with the K in a pure buffer. The precise molecular mechanisms of these profound changes are not...

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Detalles Bibliográficos
Autores principales: Bielec, Krzysztof, Kowalski, Adam, Bubak, Grzegorz, Witkowska Nery, Emilia, Hołyst, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762655/
https://www.ncbi.nlm.nih.gov/pubmed/34962392
http://dx.doi.org/10.1021/acs.jpclett.1c03596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762655/
https://www.ncbi.nlm.nih.gov/pubmed/34962392
http://dx.doi.org/10.1021/acs.jpclett.1c03596

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