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Ion Complexation Explains Orders of Magnitude Changes in the Equilibrium Constant of Biochemical Reactions in Buffers Crowded by Nonionic Compounds
[Image: see text] The equilibrium constant (K) of biochemical complex formation in aqueous buffers with high concentration (>20 wt %) of nonionic compounds can vary by orders of magnitude in comparison with the K in a pure buffer. The precise molecular mechanisms of these profound changes are not...
Autores principales: | Bielec, Krzysztof, Kowalski, Adam, Bubak, Grzegorz, Witkowska Nery, Emilia, Hołyst, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762655/ https://www.ncbi.nlm.nih.gov/pubmed/34962392 http://dx.doi.org/10.1021/acs.jpclett.1c03596 |
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