Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells

[Image: see text] Plasmodium falciparum causes the most lethal form of malaria. Peroxide antimalarials based on artemisinin underpin the frontline treatments for malaria, but artemisinin resistance is rapidly spreading. Synthetic peroxide antimalarials, known as ozonides, are in clinical development...

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Detalles Bibliográficos
Autores principales: Siddiqui, Ghizal, Giannangelo, Carlo, De Paoli, Amanda, Schuh, Anna Katharina, Heimsch, Kim C., Anderson, Dovile, Brown, Timothy G., MacRaild, Christopher A., Wu, Jianbo, Wang, Xiaofang, Dong, Yuxiang, Vennerstrom, Jonathan L., Becker, Katja, Creek, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762662/
https://www.ncbi.nlm.nih.gov/pubmed/34985858
http://dx.doi.org/10.1021/acsinfecdis.1c00550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762662/
https://www.ncbi.nlm.nih.gov/pubmed/34985858
http://dx.doi.org/10.1021/acsinfecdis.1c00550

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