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Malondialdehyde-Modified Photoreceptor Outer Segments Promote Choroidal Neovascularization in Mice

PURPOSE: This study aimed to establish a novel choroidal neovascularization (CNV) mouse model through subretinally injecting malondialdehyde (MDA)-modified photoreceptor outer segments (POS), which was more consistent with the pathogenesis of wet age-related macular degeneration (AMD). METHODS: MDA-...

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Detalles Bibliográficos
Autores principales: Chen, Yuhong, Zhu, Xinyue, Ye, Fuxiang, Wang, Hong, Wan, Xiaoling, Zhang, Ting, Wang, Yuwei, Wang, Yimin, Zhao, Xiaohuan, Bai, Xinyue, Xiao, Yushu, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762676/
https://www.ncbi.nlm.nih.gov/pubmed/35015060
http://dx.doi.org/10.1167/tvst.11.1.12