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Amide Bond Formation via the Rearrangement of Nitrile Imines Derived from N-2-Nitrophenyl Hydrazonyl Bromides

[Image: see text] We report how the rearrangement of highly reactive nitrile imines derived from N-2-nitrophenyl hydrazonyl bromides can be harnessed for the facile construction of amide bonds. This amidation reaction was found to be widely applicable to the synthesis of primary, secondary, and tert...

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Detalles Bibliográficos
Autores principales: Boyle, Mhairi, Livingstone, Keith, Henry, Martyn C., Elwood, Jessica M. L., Lopez-Fernandez, J. Daniel, Jamieson, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762704/
https://www.ncbi.nlm.nih.gov/pubmed/34964648
http://dx.doi.org/10.1021/acs.orglett.1c03993