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Dimerization of SARS-CoV-2 nucleocapsid protein affects sensitivity of ELISA based diagnostics of COVID-19

Nucleocapsid protein (N protein) is the primary antigen of the virus for development of sensitive diagnostic assays of COVID-19. In this paper, we demonstrate the significant impact of dimerization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) N-protein on sensitivity of enzyme...

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Detalles Bibliográficos
Autores principales: Khan, Wajihul Hasan, Khan, Nida, Mishra, Avinash, Gupta, Surbhi, Bansode, Vikrant, Mehta, Deepa, Bhambure, Rahul, Ansari, M. Ahmad, Das, Shukla, Rathore, Anurag S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762837/
https://www.ncbi.nlm.nih.gov/pubmed/35051498
http://dx.doi.org/10.1016/j.ijbiomac.2022.01.094