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Intestinal Claudin-7 deficiency impacts the intestinal microbiota in mice with colitis

BACKGROUND: Intestinal epithelial cells form a physical barrier that protects the intestine against the intestinal microbiota through tight junctions (TJs) and adhesive junctions, while barrier disruption may lead to inflammatory bowel disease (IBD). Claudin-7 (Cldn7) has been implicated in this pro...

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Detalles Bibliográficos
Autores principales: Ding, Yuhan, Wang, Kun, Xu, Chang, Hao, Mengdi, Li, Huimin, Ding, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762895/
https://www.ncbi.nlm.nih.gov/pubmed/35039003
http://dx.doi.org/10.1186/s12876-022-02100-8