Single-cell trajectories of melanoma cell resistance to targeted treatment

OBJECTIVE: Cellular heterogeneity is regarded as a major factor affecting treatment response and resistance in malignant melanoma. Recent developments in single-cell sequencing technology have provided deeper insights into these mechanisms. METHODS: Here, we analyzed a BRAF(V600E)-mutant melanoma ce...

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Detalles Bibliográficos
Autores principales: Schmidt, Maria, Mortensen, Lena Sünke, Loeffler-Wirth, Henry, Kosnopfel, Corinna, Krohn, Knut, Binder, Hans, Kunz, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763000/
https://www.ncbi.nlm.nih.gov/pubmed/34591417
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763000/
https://www.ncbi.nlm.nih.gov/pubmed/34591417
http://dx.doi.org/10.20892/j.issn.2095-3941.2021.0267

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