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Guide RNA acrobatics: the one-for-two shuffle
RNA modifications are crucial for the proper function of the RNAs. The sites of pseudouridines are often specified by dual hairpin guide RNAs, with one or both hairpins identifying a target uridine. In this issue of Genes & Development, Jády and colleagues (pp. 70–83) identify a novel mechanism...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763051/ https://www.ncbi.nlm.nih.gov/pubmed/35022325 http://dx.doi.org/10.1101/gad.349285.121 |