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Guide RNA acrobatics: the one-for-two shuffle

RNA modifications are crucial for the proper function of the RNAs. The sites of pseudouridines are often specified by dual hairpin guide RNAs, with one or both hairpins identifying a target uridine. In this issue of Genes & Development, Jády and colleagues (pp. 70–83) identify a novel mechanism...

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Detalles Bibliográficos
Autor principal: Meier, U. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763051/
https://www.ncbi.nlm.nih.gov/pubmed/35022325
http://dx.doi.org/10.1101/gad.349285.121