Synthesis of Novel Suramin Analogs With Anti-Proliferative Activity via FGF1 and FGFRD2 Blockade

A promising approach in cancer therapy is the inhibition of cell proliferation using small molecules. In this study, we report the synthesis of suramin derivatives and their applications. We used NMR spectroscopy and docking simulations to confirm binding sites and three-dimensional models of the li...

Descripción completa

Detalles Bibliográficos
Autores principales: Parveen, Nuzhat, Lin, Yan-Liang, Chou, Ruey-Hwang, Sun, Chung-Ming, Yu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763243/
https://www.ncbi.nlm.nih.gov/pubmed/35047478
http://dx.doi.org/10.3389/fchem.2021.764200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763243/
https://www.ncbi.nlm.nih.gov/pubmed/35047478
http://dx.doi.org/10.3389/fchem.2021.764200

Ejemplares similares