2-Sulfonylpyrimidines as Privileged Warheads for the Development of S. aureus Sortase A Inhibitors

Staphylococcus aureus is one of the most frequent causes of nosocomial and community-acquired infections, with emerging multiresistant isolates causing a significant burden to public health systems. We identified 2-sulfonylpyrimidines as a new class of potent inhibitors against S. aureus sortase A a...

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Detalles Bibliográficos
Autores principales: Barthels, Fabian, Meyr, Jessica, Hammerschmidt, Stefan J., Marciniak, Tessa, Räder, Hans-Joachim, Ziebuhr, Wilma, Engels, Bernd, Schirmeister, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763382/
https://www.ncbi.nlm.nih.gov/pubmed/35047562
http://dx.doi.org/10.3389/fmolb.2021.804970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763382/
https://www.ncbi.nlm.nih.gov/pubmed/35047562
http://dx.doi.org/10.3389/fmolb.2021.804970

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