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Reduced amplification efficiency of the RNA-dependent-RNA-polymerase target enables tracking of the Delta SARS-CoV-2 variant using routine diagnostic tests

Routine SARS-CoV-2 surveillance in the Western Cape region of South Africa (January-August 2021) found a reduced RT-PCR amplification efficiency of the RdRp-gene target of the Seegene, Allplex 2019-nCoV diagnostic assay from June 2021 when detecting the Delta variant. We investigated whether the red...

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Detalles Bibliográficos
Autores principales: Valley-Omar, Ziyaad, Marais, Gert, Iranzadeh, Arash, Naidoo, Michelle, Korsman, Stephen, Maponga, Tongai, Hussey, Hannah, Davies, Mary-Ann, Boulle, Andrew, Doolabh, Deelan, Laubscher, Mariska, Wojno, Justyna, Deetlefs, J.D., Maritz, Jean, Scott, Lesley, Msomi, Nokukhanya, Naicker, Cherise, Tegally, Houriiyah, de Oliveira, Tulio, Bhiman, Jinal, Williamson, Carolyn, Preiser, Wolfgang, Hardie, Diana, Hsiao, Nei-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763409/
https://www.ncbi.nlm.nih.gov/pubmed/35051442
http://dx.doi.org/10.1016/j.jviromet.2022.114471