Heme Oxygenase-1 Inhibits the Proliferation of Hepatic Stellate Cells by Activating PPARγ and Suppressing NF-κB

BACKGROUND: Hepatic stellate cells (HSCs) are reported to play significant roles in the development of liver fibrosis. Heme oxygenase-1 (HO-1) is a key rate-limiting enzyme, which could decrease collagen synthesis and liver damage. Nevertheless, it was yet elusive towards the function and mechanism...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Zhang, Li, Chen, Jie, Zhang, Xiaoqian, Zhao, Zhongfu, Zhao, Longfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763483/
https://www.ncbi.nlm.nih.gov/pubmed/35047060
http://dx.doi.org/10.1155/2022/8920861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763483/
https://www.ncbi.nlm.nih.gov/pubmed/35047060
http://dx.doi.org/10.1155/2022/8920861

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