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Ligustrazine Inhibits Lung Phosphodiesterase Activity in a Rat Model of Allergic Asthma

OBJECTIVES: This study sought to examine whether ligustrazine was capable of inhibiting phosphodiesterase (PDE) activity and improving lung function in a rat model of asthma. METHODS: Rats were initially sensitized using ovalbumin (OVA) and then were challenged daily with aerosolized OVA beginning 1...

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Detalles Bibliográficos
Autores principales: Wang, Yajuan, Zhu, Huizhi, Tong, Jiabing, Li, Zegeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763486/
https://www.ncbi.nlm.nih.gov/pubmed/35047052
http://dx.doi.org/10.1155/2022/1452116