3β,23-Dihydroxy-12-ene-28-ursolic Acid Isolated from Cyclocarya paliurus Alleviates NLRP3 Inflammasome-Mediated Gout via PI3K-AKT-mTOR-Dependent Autophagy

Gout is regarded as a painful inflammatory arthritis induced by the deposition of monosodium urate crystals in joints and soft tissues. Nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome-mediated IL-1β production plays a crucial role i...

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Detalles Bibliográficos
Autores principales: Lou, Dongxiao, Zhang, Xiaogai, Jiang, Cuihua, Zhang, Fang, Xu, Chao, Fang, Shengzuo, Shang, Xulan, Zhang, Jian, Yin, Zhiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763513/
https://www.ncbi.nlm.nih.gov/pubmed/35047046
http://dx.doi.org/10.1155/2022/5541232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763513/
https://www.ncbi.nlm.nih.gov/pubmed/35047046
http://dx.doi.org/10.1155/2022/5541232

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