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Melatonin Attenuates Ischemia/Reperfusion-Induced Oxidative Stress by Activating Mitochondrial Fusion in Cardiomyocytes

Myocardial ischemia/reperfusion (I/R) injury can stimulate mitochondrial reactive oxygen species production. Optic atrophy 1- (OPA1-) induced mitochondrial fusion is an endogenous antioxidative mechanism that preserves the mitochondrial function. In our study, we investigated whether melatonin augme...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoling, Wang, Shengchi, Cheng, Hui, Ouyang, Haichun, Ma, Xiaoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763517/
https://www.ncbi.nlm.nih.gov/pubmed/35047108
http://dx.doi.org/10.1155/2022/7105181