Analysis of 272 Genetic Variants in the Upgraded Interactive FXI Web Database Reveals New Insights into FXI Deficiency

Coagulation Factor XI (FXI) is a plasma glycoprotein composed of four apple (Ap) domains and a serine protease (SP) domain. FXI circulates as a dimer and activates Factor IX (FIX), promoting thrombin production and preventing excess blood loss. Genetic variants that degrade FXI structure and functio...

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Detalles Bibliográficos
Autores principales: Harris, Victoria A., Lin, Weining, Perkins, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763576/
https://www.ncbi.nlm.nih.gov/pubmed/35059554
http://dx.doi.org/10.1055/a-1683-8605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763576/
https://www.ncbi.nlm.nih.gov/pubmed/35059554
http://dx.doi.org/10.1055/a-1683-8605

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