A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals

Our previous big data analyses showed a high level of association between chitinase 3 like1 (CHI3L1) expression and lung tumor development. In the present study, we investigated whether a CHI3L1‐inhibiting chemical, 2‐({3‐[2‐(1‐cyclohexen‐1‐yl)ethyl]‐6,7‐dimethoxy‐4‐oxo‐3,4‐dihydro‐2‐quinazolinyl}su...

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Detalles Bibliográficos
Autores principales: Lee, Yong Sun, Yu, Ji Eun, Kim, Ki Cheon, Lee, Dong Hun, Son, Dong Ju, Lee, Hee Pom, Jung, Jae‐kyung, Kim, Nam Du, Ham, Young Wan, Yun, Jaesuk, Han, Sang‐Bae, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763653/
https://www.ncbi.nlm.nih.gov/pubmed/34758182
http://dx.doi.org/10.1002/1878-0261.13138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763653/
https://www.ncbi.nlm.nih.gov/pubmed/34758182
http://dx.doi.org/10.1002/1878-0261.13138

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