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A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals
Our previous big data analyses showed a high level of association between chitinase 3 like1 (CHI3L1) expression and lung tumor development. In the present study, we investigated whether a CHI3L1‐inhibiting chemical, 2‐({3‐[2‐(1‐cyclohexen‐1‐yl)ethyl]‐6,7‐dimethoxy‐4‐oxo‐3,4‐dihydro‐2‐quinazolinyl}su...
Autores principales: | Lee, Yong Sun, Yu, Ji Eun, Kim, Ki Cheon, Lee, Dong Hun, Son, Dong Ju, Lee, Hee Pom, Jung, Jae‐kyung, Kim, Nam Du, Ham, Young Wan, Yun, Jaesuk, Han, Sang‐Bae, Hong, Jin Tae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763653/ https://www.ncbi.nlm.nih.gov/pubmed/34758182 http://dx.doi.org/10.1002/1878-0261.13138 |
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