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Recombinant nanobody against MUC1 tandem repeats inhibits growth, invasion, metastasis, and vascularization of spontaneous mouse mammary tumors

Alteration in glycosylation pattern of MUC1 mucin tandem repeats during carcinomas has been shown to negatively affect adhesive properties of malignant cells and enhance tumor invasiveness and metastasis. In addition, MUC1 overexpression is closely interrelated with angiogenesis, making it a great t...

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Detalles Bibliográficos
Autores principales: Merikhian, Parnaz, Darvishi, Behrad, Jalili, Neda, Esmailinejad, Mohammad Reza, Khatibi, Azadeh Sharif, Kalbolandi, Shima Moradi, Salehi, Malihe, Mosayebzadeh, Marjan, Barough, Mahdieh Shokrollahi, Majidzadeh‐A, Keivan, Yadegari, Fatemeh, Rahbarizadeh, Fatemeh, Farahmand, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763658/
https://www.ncbi.nlm.nih.gov/pubmed/34694686
http://dx.doi.org/10.1002/1878-0261.13123