Cargando…

PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy

As a primary cause of dementia and death in older people, Alzheimer’s disease (AD) has become a common problem and challenge worldwide. Abnormal accumulation of tau proteins in the brain is a hallmark pathology of AD and is closely related to the clinical progression and severity of cognitive defici...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Xing Jun, Wu, Yan Qing, Ma, Rong, Chang, Yan Min, Li, Lu Lu, Zhu, Jia Hui, Liu, Gong Ping, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763800/
https://www.ncbi.nlm.nih.gov/pubmed/35059394
http://dx.doi.org/10.3389/fcell.2021.736267