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PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy
As a primary cause of dementia and death in older people, Alzheimer’s disease (AD) has become a common problem and challenge worldwide. Abnormal accumulation of tau proteins in the brain is a hallmark pathology of AD and is closely related to the clinical progression and severity of cognitive defici...
Autores principales: | Jiang, Xing Jun, Wu, Yan Qing, Ma, Rong, Chang, Yan Min, Li, Lu Lu, Zhu, Jia Hui, Liu, Gong Ping, Li, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763800/ https://www.ncbi.nlm.nih.gov/pubmed/35059394 http://dx.doi.org/10.3389/fcell.2021.736267 |
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