Sonic Hedgehog Pathway Modulation Normalizes Expression of Olig2 in Rostrally Patterned NPCs With Trisomy 21

The intellectual disability found in people with Down syndrome is associated with numerous changes in early brain development, including the proliferation and differentiation of neural progenitor cells (NPCs) and the formation and maintenance of myelin in the brain. To study how early neural precurs...

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Detalles Bibliográficos
Autores principales: Klein, Jenny A., Li, Zhen, Rampam, Sanjeev, Cardini, Jack, Ayoub, Amara, Shaw, Patricia, Rachubinski, Angela L., Espinosa, Joaquin M., Zeldich, Ella, Haydar, Tarik F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763807/
https://www.ncbi.nlm.nih.gov/pubmed/35058753
http://dx.doi.org/10.3389/fncel.2021.794675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763807/
https://www.ncbi.nlm.nih.gov/pubmed/35058753
http://dx.doi.org/10.3389/fncel.2021.794675

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